EMD Serono, USA
Merck KGaA, Darmstadt, Germany
Merck KGaA, Darmstadt, Germany

Gene

Gene

PERSONAL VISION
PERSONAL VISION  
Gene’s graduate advisor and mentor was a pioneer in the field of interferon and cytokine research. His vision that the study of cytokine biology could lead to effective treatments for a variety of human ailments pointed the way for Gene to pursue a career in biopharma. Gene is conscious of the fact that by doing good science, he may contribute to saving lives—a perspective that is at times both energizing and humbling.
Gene enjoys being a part of an organization wholly dedicated to improving the quality of human lives through innovative science and sound business strategies. While there are many workplaces in the Boston area to choose from, EMD Serono stands out to Gene as a company that continues to grow with a clear focus and commitment to its customers and employees.
As part of the R&D organization, Gene finds it gratifying to see his work contribute in a tangible way to moving exciting new products into the clinic. He is proud to be part of an organization that values and encourages innovation and helps its employees bring better products forward more efficiently.
Education
Carnegie Mellon University. BS, Biology (1988)
NYU School of Medicine. MS, PhD, Microbiology (1993)
Postdoctoral
Dana-Farber Cancer Institute, Harvard Medical School (1995)
Publications
Cacciuttolo M, Lee GW, Chon J, Lewis J. Gene Expression, Human Cells. Wiley Encyclopedia of Industrial Biotechnology. 2009 (manuscript in preparation).
Tchoudakova A, Hensel F, Murillo A, Eng B, Foley M, Smith L, Schoenen F, Hildebrand A, Kelter A-R, Ilag LL, Vollmers HP, Brandlein S, McIninch J, Chon J, Lee GW, Cacciuttolo M. High level expression of functional IgMs in the PER.C6 human cell line. Mabs. 2009;1(2):163-171.
Lee GW. Stabilizing protein-folding conformations. Genetic Engineering News. 2008 March 11;60-63.
Lee GW, Fecko JK, Yen A, Donaldson D, Wood C, Tobler S, Vunuum S, Luo Y, Leonard M. Improving the expression of a soluble receptor: Fc fusion protein in CHO cells by coexpression with the receptor ligand. Cell Technology for Cell Products. 2007: 29-39.
Li W, Kedersha N, Chen S, Gilks N, Lee G, Anderson P. FAST is a BCL-X(L)-associated mitochondrial protein. Biochem Biophys Res Commun. 2004;318(1):95-102.
Lee GW, Melchior F, Matunis M, Mahajan R, Tian Q, Anderson P. Modification of Ran GTPase-activating protein by the small ubiquitin-like modifier SUMO-1 requires Ubc9, an E2-like ubiquitin conjugating enzyme homologue. J Biol Chem 1998;273:6503- 6507.
Lee GW, Goodman AR, Lee TH, Vilcek J. Relationship of TSG-14 protein to the pentraxin family of major acute phase proteins. J Immunol. 1994;153:3700-3703.
Lee GW, Lee, TH, Vilcek J. TSG-14, a TNF- and IL-1-inducible protein, is a novel member of the pentaxin family of acute phase proteins. J Immunol. 1993;150:1804-1812.